Rauwolscine Hydrochloride (Alpha Yohimbine HCl) is an indole alkaloid salt commonly utilized in analytical laboratories for chemical characterization, reference standard development, chromatographic validation, stereochemical analysis, and alkaloid research. Rauwolscine is a stereoisomer within the yohimban alkaloid family, and conversion to its hydrochloride salt provides a well-defined crystalline form suitable for laboratory handling, solution preparation, and instrumental analysis. Its characteristic pentacyclic indole framework and defined stereochemistry make it particularly useful for comparative alkaloid analysis and analytical method development. IsoPep Sciences supplies this material exclusively as a laboratory research chemical for analytical and scientific investigation.
Chemical Name: Rauwolscine Hydrochloride
IUPAC Name: Methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate hydrochloride
CAS Number: 6211-32-1
Molecular Formula: C21H27ClN2O3
Molecular Weight: 390.90 g/mol
Chemical Class: Indole alkaloid hydrochloride
Synonyms:
Appearance: White to off-white crystalline solid
Purity: Refer to batch-specific Certificate of Analysis
Rauwolscine hydrochloride is a pentacyclic indole alkaloid possessing the characteristic yohimban molecular framework. Its structure incorporates an indole nucleus fused to multiple saturated heterocyclic and carbocyclic rings, together with a methyl ester, hydroxyl functionality, and a tertiary amine present in its hydrochloride salt form.
Rauwolscine is structurally related to yohimbine but possesses a distinct stereochemical configuration. This stereochemical distinction is analytically significant because compounds sharing the same molecular formula and closely related connectivity may exhibit different chromatographic retention characteristics, spectroscopic signatures, crystallization behavior, and physicochemical properties.
The hydrochloride form consists of the rauwolscine molecular framework associated with hydrochloric acid, producing a molecular formula of C21H27ClN2O3 and a molecular weight of approximately 390.90 g/mol. The salt form can also influence solubility, crystallinity, and analytical handling relative to the corresponding free-base material.
Typical laboratory characterization may include:
Because rauwolscine belongs to a family of closely related yohimban alkaloids, chromatographic and spectroscopic methods capable of distinguishing structurally related compounds and stereoisomers may be particularly useful during identity and purity assessment.
Batch-specific Certificates of Analysis should be referenced when available.
This product is supplied exclusively for legitimate laboratory research, analytical testing, and scientific investigation. It is not intended for human consumption, veterinary use, therapeutic applications, food use, cosmetic use, or household use. Researchers are responsible for handling this material in accordance with applicable laboratory safety procedures and regulations.
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