Rauwolscine (Alpha Yohimbine) HCl | CAS: 6211-32-1 | 1 Gram

Rauwolscine Hydrochloride (Alpha Yohimbine HCl), CAS 6211-32-1, is a high-purity indole alkaloid research chemical supplied in a 1-gram format for laboratory analytical and scientific investigation.

$29.99

200 in stock

Rauwolscine Hydrochloride (Alpha Yohimbine HCl) is an indole alkaloid salt commonly utilized in analytical laboratories for chemical characterization, reference standard development, chromatographic validation, stereochemical analysis, and alkaloid research. Rauwolscine is a stereoisomer within the yohimban alkaloid family, and conversion to its hydrochloride salt provides a well-defined crystalline form suitable for laboratory handling, solution preparation, and instrumental analysis. Its characteristic pentacyclic indole framework and defined stereochemistry make it particularly useful for comparative alkaloid analysis and analytical method development. IsoPep Sciences supplies this material exclusively as a laboratory research chemical for analytical and scientific investigation.


Chemical Profile

Chemical Name: Rauwolscine Hydrochloride

IUPAC Name: Methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate hydrochloride

CAS Number: 6211-32-1

Molecular Formula: C21H27ClN2O3

Molecular Weight: 390.90 g/mol

Chemical Class: Indole alkaloid hydrochloride

Synonyms:

  • Rauwolscine HCl
  • Rauwolscine Hydrochloride
  • Alpha Yohimbine Hydrochloride
  • α-Yohimbine Hydrochloride
  • α-Yohimbin Hydrochloride
  • Isoyohimbine Hydrochloride
  • NSC 407307

Appearance: White to off-white crystalline solid

Purity: Refer to batch-specific Certificate of Analysis


Structural Characteristics

Rauwolscine hydrochloride is a pentacyclic indole alkaloid possessing the characteristic yohimban molecular framework. Its structure incorporates an indole nucleus fused to multiple saturated heterocyclic and carbocyclic rings, together with a methyl ester, hydroxyl functionality, and a tertiary amine present in its hydrochloride salt form.

Rauwolscine is structurally related to yohimbine but possesses a distinct stereochemical configuration. This stereochemical distinction is analytically significant because compounds sharing the same molecular formula and closely related connectivity may exhibit different chromatographic retention characteristics, spectroscopic signatures, crystallization behavior, and physicochemical properties.

The hydrochloride form consists of the rauwolscine molecular framework associated with hydrochloric acid, producing a molecular formula of C21H27ClN2O3 and a molecular weight of approximately 390.90 g/mol. The salt form can also influence solubility, crystallinity, and analytical handling relative to the corresponding free-base material.


Analytical Considerations

Typical laboratory characterization may include:

  • High-Performance Liquid Chromatography (HPLC)
  • Ultra-Performance Liquid Chromatography (UPLC)
  • Liquid Chromatography–Mass Spectrometry (LC-MS)
  • Gas Chromatography–Mass Spectrometry (GC-MS), where method conditions are appropriate
  • Proton Nuclear Magnetic Resonance (^1H NMR)
  • Carbon-13 Nuclear Magnetic Resonance (^13C NMR)
  • Fourier Transform Infrared Spectroscopy (FTIR)
  • Ultraviolet-Visible Spectroscopy (UV-Vis)
  • High-Resolution Mass Spectrometry (HRMS)
  • Melting point analysis
  • Chiral chromatographic analysis for stereochemical differentiation

Because rauwolscine belongs to a family of closely related yohimban alkaloids, chromatographic and spectroscopic methods capable of distinguishing structurally related compounds and stereoisomers may be particularly useful during identity and purity assessment.

Batch-specific Certificates of Analysis should be referenced when available.


Handling & Storage

  • Store in a tightly sealed container.
  • Protect from excessive heat, moisture, and direct sunlight.
  • Store in a cool, dry environment.
  • Minimize unnecessary exposure to ambient moisture during laboratory handling.
  • Handle using appropriate laboratory PPE.
  • Avoid inhalation of dust and direct skin or eye contact.
  • Use only in properly equipped laboratory environments.
  • Consult the applicable Safety Data Sheet (SDS) before handling.

Research Use Disclaimer

This product is supplied exclusively for legitimate laboratory research, analytical testing, and scientific investigation. It is not intended for human consumption, veterinary use, therapeutic applications, food use, cosmetic use, or household use. Researchers are responsible for handling this material in accordance with applicable laboratory safety procedures and regulations.